Twogee Biotech

Every harvest leaves behind vast quantities of straw, stalks, husks, and other plant residues. While these materials contain valuable carbon-rich compounds, much of their potential remains locked within complex lignocellulosic structures that remain difficult to process efficiently. As industries seek alternatives to fossil-based raw materials, interest is growing in technologies capable of unlocking these underutilised resources. Munich-based startup Twogee Biotech develops customised enzyme solutions designed to convert agricultural and industrial biomass side streams into valuable feedstocks for biotechnology and sustainable manufacturing. By combining custom-fit enzyme cocktails, industrial production stains, circular economy principles and tech-licensing for cost-effective on-site enzyme production, the company provides economic solutions to transform low-value side streams into building blocks for the emerging bioeconomy.

Technology and Product

Breaking down lignocellulosic biomass efficiently requires highly specialised biological tools. Twogee develops customised enzyme solutions tailored to specific feedstocks and industrial requirements. The company combines enzyme screening, strain development, as well as fermentation and hydrolysis process developments predictive to customer-scales to improve the conversion of agricultural residues and industrial side streams into usable intermediates. According to Twogee, its approach is designed to accelerate process development while enabling more efficient utilisation of diverse lignocellulosic feedstocks. The current development activities focus on solutions enabling second-generation sugars and other bio-based feedstocks for downstream applications in biotechnology and synthetic biology.

Twogee combines enzyme engineering and bioprocess development to unlock value from underutilised biomass streams. (© Twogee Biotech)

Industrial Fit and Applications

Many bio-based industries face the challenge of securing sustainable carbon sources without competing with food production. Twogee addresses this challenge by focusing on agricultural residues such as wheat straw, corn stover, bagasse, and other lignocellulosic side streams. The resulting second-generation feedstocks can support applications in industrial biotechnology, synthetic biology, bio-based chemicals, and advanced materials manufacturing. In addition to technology development, the company is exploring licensing approaches intended to enable local enzyme production and decentralised biomass processing, supporting regional circular value chains and improved resource efficiency.

Agricultural by-products and lignocellulosic residues assessed for conversion into second-generation bio-based feedstocks. (© Twogee Biotech)

Founding Team

Twogee Biotech was founded in 2024 by Dr. Frank Wallrapp and Dr. Helge Jochens, who bring more than a decade of experience in industrial biotechnology, enzyme development, and fermentation technologies. Emerging from Munich’s biotechnology ecosystem and supported by the BioM MAxL Incubator, the team combines expertise in enzyme engineering, process development, industrial scale-up, and commercial biotechnology.